An inositol phosphate with antioxidant and anticancer activities; chelates iron at a molar ratio of 1:4 to reduce iron-induced hydroxy radical production and lipid peroxidation in cell-free assays; inhibits TBARS formation in cooked chicken breast at 1.5 mM; inhibits proliferation of a variety of cancer cells in vitro and reduces tumor growth in rodent xenograft models; an anti-nutrient that binds minerals in grains

D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (sodium salt) – 500 µg

Brand:
Cayman
CAS:
34367-89-0
Storage:
-20
UN-No:
Non-Hazardous - /

D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (IP6) is a phosphate ester of inositol. It is found in mammalian cells and undergoes interconversion to other forms of inositol phosphate that act as second messengers in cell signaling.{48091} IP6 is an antioxidant that chelates iron at a molar ratio of 1:4 to reduce iron-induced hydroxy radical production and lipid peroxidation in cell-free assays.{48092} It also inhibits the formation of thiobarbituric acid reacting substances (TBARS) in cooked chicken breast when used at a concentration of 1.5 mM. IP6 inhibits proliferation of a variety of cancer cells in vitro and reduces tumor growth in rodent xenograft models.{48093} It is also known as phytic acid and is considered an anti-nutrient that binds minerals, including calcium, iron, magnesium, and zinc, in grains, legumes, oilseeds, nuts, and other plants and prevents their absorption in the gastrointestinal tract of humans and animals that ingest them.{48091} Formulations containing IP6 have been used in cosmetics and as preservatives in food production. Cayman’s IP6 is a highly purified product intended for use in biomedical research applications.  

 

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SKU: 10008415 - 500 µg Category:

Description

An inositol phosphate with antioxidant and anticancer activities; chelates iron at a molar ratio of 1:4 to reduce iron-induced hydroxy radical production and lipid peroxidation in cell-free assays; inhibits TBARS formation in cooked chicken breast at 1.5 mM; inhibits proliferation of a variety of cancer cells in vitro and reduces tumor growth in rodent xenograft models; an anti-nutrient that binds minerals in grains, legumes, oilseeds, nuts, and other plants and prevents their absorption in the gastrointestinal tract

Formal name: myo-inositol, 1,2,3,4,5,6-hexakis(dihydrogen phosphate), hexasodium salt

Synonyms:  IP6|Phytic Acid

Molecular weight: 791.9

CAS: 34367-89-0

Purity: ≥98%

Formulation: A lyophilized powder

Product Type|Biochemicals|Metal Chelators||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation

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