Description
An inhibitor of alkaline ceramidase (Ki = 2-13 µM; IC50 = 1-5 µM); selective for alkaline ceramidase over acid ceramidase (IC50 = >500 µM) as well as CAPP at 0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells ,
Formal name: N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrien-1-yl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2E,4E,6R-trimethyl-2,4-decadienamide
Synonyms: (1S,2R-D-erythro-2-N-myristoylamino)-1-phenyl-1-propanol
Molecular weight: 361.6
CAS: 143492-38-0
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Small Molecule Inhibitors|Sphingolipid Turnover||Research Area|Cancer|Cell Cycle|G1||Research Area|Lipid Biochemistry|Sphingolipids
