An inhibitor of SAAH (IC50 = 7 nM); inhibits growth of C. parvum parasites (MIC50 = 3 μM) without exhibiting cytotoxicity in HCT-8 cells (CC50 = >1 mM); dietary administration increases liver microsomal phosphatidylethanolamine concentration and decreases liver microsomal Δ6 desaturase activity and plasma cholesterol levels in rats at 50 mg/kg

D-Eritadenine – 5 mg

Brand:
Cayman
CAS:
23918-98-1
Storage:
-20
UN-No:
Non-Hazardous - /

D-Eritadenine is an adenosine analog and a potent, reversible inhibitor of S-adenosylhomocysteine hydrolase (SAAH; IC50 = 7 nM).{46113} It inhibits growth of C. parvum parasites (MIC50 = 3 μM) without exhibiting cytotoxicity in HCT-8 cells (CC50 = >1 mM).{46114} Dietary administration of D-eritadenine (50 mg/kg) increases liver microsomal phosphatidylethanolamine concentration and decreases liver microsomal Δ6 desaturase activity and plasma cholesterol levels in rats.{46115}  

 

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Description

An inhibitor of SAAH (IC50 = 7 nM); inhibits growth of C. parvum parasites (MIC50 = 3 μM) without exhibiting cytotoxicity in HCT-8 cells (CC50 = >1 mM); dietary administration increases liver microsomal phosphatidylethanolamine concentration and decreases liver microsomal Δ6 desaturase activity and plasma cholesterol levels in rats at 50 mg/kg ,

Formal name: 6-amino-αR,βR-dihydroxy-9H-purine-9-butanoic acid

Synonyms: 

Molecular weight: 253.2

CAS: 23918-98-1

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Nucleotides/Nucleosides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

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