Description
An LRRK2 inhibitor with IC50s = 1.28 and 1.85 nM for wild-type and G2019S mutant forms of LRRK2, respectively; protects against neuronal injury induced by LRRK2-G2019S mutant activity in primary human neurons (EC50 = 1 nM)
Formal name: N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-methanesulfonamide
Synonyms:
Molecular weight: 505
CAS: 1191911-27-9
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Kinase Inhibitors|Other Serine/Threonine Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease||Research Area|Neuroscience|Neuroprotection
