Description
This pan-cytokeratin antibody detects cytokeratin isoforms 4, 5, 6, 8, 10, 13, and 18.{11908} Cytokeratins make up a large family of proteins classified as intermediate filament polypeptides.{11908,15722} They are subdivided into type I (acidic) and type II (basic/neutral) proteins.{15723} Under normal conditions, these proteins are found in epithelial cells as type I/type II pairs.{11908,15740} These pairs provide cellular support as well as contributing to more dynamic processes. Cytokeratins undergo extensive post translational modifications, such as phosphorylation, and are differentially expressed in normal and cancer cells.{15740,15721}
Synonyms: pan-Cytokeratin
Immunogen:
Formulation: 100 µg of protein A-purified, fluorescein-labeled monoclonal antibody
Isotype:
Applications: FC and IF
Origin: Animal/Mouse
Stability: 365 days
Application|Flow Cytometry||Application|Immunofluorescence||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cancer||Research Area|Cell Biology|Cytoskeleton & Motor Proteins||Research Area|Endocrinology & Metabolism
