Inhibits actin polymerization; potently and selectively inhibits the growth of endothelial cells (IC50 1 protease activity

Cytochalasin E – 5 mg

Brand:
Cayman
CAS:
36011-19-5
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization.{21305,21310,21312,21316} This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion.{21307,21313,21306,21315} Cytochalasin E is an epoxide-containing analog of cytochalasin B (Item No. 11328) which potently and selectively inhibits the growth of endothelial cells (IC50 1 protease activity.{21309,21308,21211}  

 

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SKU: 11331 - 5 mg Category:

Description

Inhibits actin polymerization; potently and selectively inhibits the growth of endothelial cells (IC50 1 protease activity

Formal name: (1E,4S,6R,7E,11aS,14S,14aS,15S,15aR,16aS,16bS)-3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-[1,3]dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione

Synonyms:  NSC 175151

Molecular weight: 495.6

CAS: 36011-19-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cancer|Angiogenesis||Research Area|Cell Biology|Cytoskeleton & Motor Proteins

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