A cell-permeable inhibitor that binds actin filaments

Cytochalasin D – 5 mg

Brand:
Cayman
CAS:
22144-77-0
Storage:
-20
UN-No:
De Minimis - 1544 / 6.1

The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization.{21305,21310,21312,21316} This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion.{21307,21313,21306,21315} Cytochalasin D is a cell-permeable inhibitor that binds actin filaments, but not actin monomers, to inhibit polymerization at concentrations as low as 0.2 µM.{21310} In this way, it prevents the migration of tumor cells.{15841}  

 

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SKU: 11330 - 5 mg Category:

Description

A cell-permeable inhibitor that binds actin filaments, but not actin monomers, to inhibit polymerization at concentrations as low as 0.2 µM

Formal name: (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1,11(2H)-dione

Synonyms:  NSC 209835

Molecular weight: 507.6

CAS: 22144-77-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Cell Biology|Cytoskeleton & Motor Proteins

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