An internal standard for the quantification of cyclophosphamide by GC- or LC-MS

Cyclophosphamide-d4 – 1 mg

Brand:
Cayman
CAS:
173547-45-0
Storage:
-20
UN-No:
De Minimis - 3464 / 6.1

Cyclophosphamide-d4 contains four deuterium atoms. It is intended for use as an internal standard for the quantification of cyclophosphamide (Item No. 13849) by GC- or LC-MS. Cyclophosphamide is a nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders.{21842,21833} In cells with low levels of aldehyde dehydrogenase, cyclophosphamide acts as a prodrug and is metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death.{22688,20436}  

 

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Description

An internal standard for the quantification of cyclophosphamide by GC- or LC-MS,

Formal name: N,N-bis(2-chloroethyl)tetrahydro-4,5-d2-2H-1,3,2-oxazaphosphorin-4,5-d2-2-amine 2-oxide

Synonyms:  Endoxan-d4

Molecular weight: 265.1

CAS: 173547-45-0

Purity: ≥99% deuterated forms (d1-d4)

Formulation: A solid

Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Research Area|Cancer|Cell Death||Research Area|Cancer|DNA Damage and Repair||Research Area|Immunology & Inflammation|Autoimmunity

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