An affinity probe for Aβ; has high affinity for Aβ (Kd = 38 nM); exhibits a 70-fold increase in fluorescence intensity

CRANAD 2 – 1 mg

Brand:
Cayman
CAS:
1193447-34-5
Storage:
-20
UN-No:
Non-Hazardous - /

CRANAD 2 is a curcumin derivative and non-conjugated affinity probe for the detection of amyloid-β (Aβ) deposits in vitro and in vivo.{40031,40032} It has high affinity for Aβ (Kd = 38 nM) and, when bound to Aβ aggregates, it exhibits a 70-fold increase in fluorescence intensity, a blue shift from 805 to 715 nm, and a large increase in quantum yield.  

 

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SKU: 19814 - Category:

Description

An affinity probe for Aβ; has high affinity for Aβ (Kd = 38 nM); exhibits a 70-fold increase in fluorescence intensity, a blue shift from 805 to 715 nm, and a large increase in quantum yield when bound to Aβ aggregates ,

Formal name: (T-4)-[(1E,6E)-1,7-bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-kO3,kO5]difluoro-boron

Synonyms: 

Molecular weight: 410.3

CAS: 1193447-34-5

Purity: ≥98%

Formulation: A crystalline solid

Application|Fluorescence||Application|TR-FRET||Product Type|Biochemicals|Labeling & Detection|Affinity Probes||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease

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