(-)-CP 55,940 – 10 mg

Brand:
Cayman
CAS:
83002-04-4
Storage:
-20
UN-No:
De Minimis - 1230 / 3|6.1

(−)-CP 55,940 is a potent and non-selective cannabinoid (CB) receptor agonist with Ki values of 0.5 to 5 and 0.69 to 2.8 nM for CB1 and CB2 receptors, respectively.{7912} It is more potent than Δ9-THC (Item Nos. 12068 | ISO60157) in both behavioral tests and in receptor binding assays.{14402} In vivo, (−)-CP 55,940 administered intraperitoneally (0.3-3 mg/kg) or as an aerosol (0.72-72 mg/ml), suppresses locomotor activity, increases tail flick latency in a hot plate test for analgesia, and decreases body temperature in mice in a dose-dependent manner.{40291} Subchronic administration of (−)-CP 55,940 (0.03 mg/kg) also reduces body weight loss and running wheel activity in a rat model of anorexia nervosa.{40292}  

 

Available on backorder

SKU: 90084 - 10 mg Category:

Description

A potent CB1 and CB2 receptor agonist (Kis = 0.58-5 and 0.69-2.8 nM for human recombinant CB1 and CB2, respectively); considerably more potent than Δ9-THC in both behavioral tests and in receptor binding assays; suppresses locomotor activity, increases tail flick latency in a hot plate test for analgesia, and decreases body temperature in mice in a dose-dependent manner; reduces body weight loss and running wheel activity in a rat model of anorexia nervosa


Formal name: 5-(1,1-dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-phenol

Synonyms: 

Molecular weight: 376.6

CAS: 83002-04-4

Purity: ≥98%

Formulation: A solution in methanol