Description
A potent EP2 receptor agonist (IC50s = 10 and 15 nM for human and rat EP2, respectively); selective for EP2 over other EP receptors (IC50s = >3,200 nM for EP1, EP3, and EP4) and a panel of 37 G protein-coupled receptors (≤30% inhibition at a concentration of 10 μM); increases cAMP in HEK293 cells expressing human EP2 (EC50 = 2.8 nM) ,
Formal name: 2-[3-[[[[4-(1H-pyrazol-1-yl)phenyl]methyl](3-pyridinylsulfonyl)amino]methyl]phenoxy]-acetic acid
Synonyms:
Molecular weight: 478.5
CAS: 752187-80-7
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience
