Description
The primary use of this antibody conjugate is for the detection of cyclooxygenase 2 (COX-2) in mouse samples by direct immunolabeling. COX catalyze the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins: the conversion of arachidonic acid to PGH2. Discoveries of the induction of COX by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothosis that the inducible form of COX, COX-2, is responsible for the biosynthesis of PGs under acute inflammatory conditions.{4,3463} COX-2 is a 72 kDa protein which has been cloned from a variety of species including human, mouse, rat, and sheep.{2,7,2284,4051}
Synonyms: Cyclooxygenase 2|PGHS2|Prostaglandin H Synthase 2
Immunogen: Synthetic peptide from the C-terminal region of mouse COX-2
Formulation: 100 µg of Fluoroscein-labeled, peptide affinity-purified IgG
Isotype:
Applications: FC, IF, and WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Flow Cytometry||Application|Fluorescence||Application|Immunofluorescence||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway
