Description
COX catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2. Recent discoveries of the induction of COX by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothosis that the inducible form of COX, COX-2, is responsible for the biosynthesis of prostaglandins under acute inflammatory conditions.{4,3463} COX-2 is a 72 kDa protein which has been cloned from a variety of species including human, mouse, rat, and sheep.{2,7,2284,4051}
Synonyms: Cyclooxygenase 2|PGHS-2|Prostaglandin H Synthase 2
Immunogen: A synthetic peptide from the C-terminal region of mouse/rat COX-2
Formulation: 500 µl peptide affinity-purified antibody
Isotype:
Applications: ICC, IF, IHC, and WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunocytochemistry||Application|Immunofluorescence||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway
