Cyclooxygenase catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2. Recent discoveries of the induction of cyclooxygenase biosynthesis by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of cyclooxygenase, COX-2, is responsible for the biosynthesis of prostaglandins under acute inflammatory conditions.{4} Cayman’s COX-2 monoclonal antibody (clone 12C10) can be used for ELISA, flow cytometry, immunofluorescence, and Western blot applications. The antibody recognizes COX-2 at 72 kDa from human, mouse, and ovine samples.
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Synonyms: Cyclooxygenase-2|PGHS-2|Prostaglandin H Synthase 2
Immunogen: Synthetic peptide from the C-terminal region of mouse COX-2
Formulation: 50 µg of protein G-purified IgG
Isotype: IgG1
Applications: ELISA, FC, IF, WB
Origin:
Stability: 365 days
Application|ELISA||Application|Flow Cytometry||Application|Immunofluorescence||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway
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