Description
This product is derived by labeling the COX-1 monoclonal antibody (Item No. 160110) with fluorescein. COX-1 catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2. COX-1 is constitutively expressed in almost all animal tissues and is involved in the homeostatic role of eicosanoids.{14,767} COX-1 is a 70 kDa protein which has been cloned from a variety of species including human, mouse, rat, and sheep.{13,300,5695,919} COX-1 from these species are approximately 90% identical at the amino acid level, whereas the homology between COX-1 and COX-2 is only about 60%.
Synonyms: Cyclooxygenase-1|PGSH-1|Prostaglandin G/H Synthase 1|Prostaglandin H2 Synthase 1|PTGS1
Immunogen: Purified ovine COX-1
Formulation: 250 µg of FITC-labeled monoclonal antibody
Isotype:
Applications: FC
Origin: Animal/Mouse
Stability: 365 days
Application|Flow Cytometry||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway
