A fluorescent probe for direct detection of peroxynitrite

Coumarin Boronic Acid – 10 mg

Brand:
Cayman
CAS:
1357078-03-5
Storage:
-20
UN-No:
Non-Hazardous - /

Coumarin boronic acid (CBA) is a fluorescent probe that can be used to detect peroxynitrite (Item No. 81565), hypochlorous acid, and hydrogen peroxide.{24619,24620,19262}It reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s) and moderately faster rate than hypochlorous acid.{24619,24620} Peroxynitrite oxidizes CBA into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively.{19262}  

 

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Description

A fluorescent probe for direct detection of peroxynitrite, hypochlorous acid, and hydrogen peroxide; reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s); COH displays ex/em = 332/470 nm, respectively

Formal name: B-(2-oxo-2H-1-benzopyran-7-yl)-boronic acid

Synonyms:  CBA

Molecular weight: 190

CAS: 1357078-03-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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