Description
A neuropeptide; structurally similar to somatostatin-28; expressed in the human brain and in interneurons of the rat hippocampus and cerebral cortex; binds to SST receptors (IC50s = 2.8, 7.1, 0.2, 3, and 13.7 nm for SST1-5, respectively); found at similar levels as cortistatin-14 in mouse AtT20 cells but secreted at a lower level
Formal name: 5-oxo-L-prolyl-L-α-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-α-aspartyl-L-lysyl-L-lysyl-L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-L-lysine, cyclic (17→28)-disulfide, trifluoroacetate salt
Synonyms:
Molecular weight: 3,540.00
CAS: 1815618-17-7
Purity: ≥95%
Formulation: A lyophilized powder
Product Type|Biochemicals|Peptides|Neuropeptides||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Glucocorticoids & Mineralocorticoids||Research Area|Neuroscience