A nucleoside analog inhibits polyadenylation when converted to cordycepin triphosphate

Cordycepin – 50 mg

Brand:
Cayman
CAS:
73-03-0
Storage:
-20
UN-No:
Non-Hazardous - 2811 / 6.1

Cordycepin is a nucleoside analog found in C. sinensis that acts as a polyadenylation inhibitor when converted to cordycepin triphosphate, which inhibits ATP-dependent DNA and RNA synthesis.{22954} Cordycepin has a broad spectrum of biological activities, including anti-proliferative, pro-apoptotic, and anti-inflammatory effects.{22954,22953,22955} Cordycepin has been shown to reduce poly(A) tail length in mRNA at 10 μM and to activate AMPK kinase, leading to a reduction in mTOR signaling at 200 μM.{22954}  

 

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Description

A nucleoside analog inhibits polyadenylation when converted to cordycepin triphosphate, which inhibits ATP-dependent DNA and RNA synthesis; produces anti-proliferative, pro-apoptotic, and anti-inflammatory effects

Formal name: 3′-deoxy-adenosine

Synonyms:  3′-Deoxyadenosine|NSC 401022|NSC 63984

Molecular weight: 251.2

CAS: 73-03-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Nucleotides/Nucleosides||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Immunology & Inflammation

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