A glycoside form of 3-demethylcolchicine; does not displace [3H]-colchicine from rat brain tubulin in vitro at 25 μM; increases CYP2C9 and CYP2E1 levels in primary human hepatocytes at 1 and 10 μM

Colchicoside – 50 mg

Brand:
Cayman
CAS:
477-29-2
Storage:
-20
UN-No:
Non-Hazardous - 2811 / 6.1

Colchicoside is a glycoside form of 3-demethylcolchicine that has been found in G. superba.{57172} Unlike cholchicine and 3-demethylcolchicine, colchicoside does not displace [3H]-colchicine from rat brain tubulin in vitro when used at a concentration of 25 μM.{57173} Colchicoside (1 and 10 μM) increases levels of the cytochrome P450 (CYP) isoforms CYP2C9 and CYP2E1 in primary human hepatocytes.{57174}  

 

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SKU: 11831 - 50 mg Category:

Description

A glycoside form of 3-demethylcolchicine; does not displace [3H]-colchicine from rat brain tubulin in vitro at 25 μM; increases CYP2C9 and CYP2E1 levels in primary human hepatocytes at 1 and 10 μM

Formal name: N-[(7S)-3-(β-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-acetamide

Synonyms:  3-Demethylcolchicine glucoside

Molecular weight: 547.6

CAS: 477-29-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Glycosides||Research Area|Toxicology|Drug Metabolism|Cytochrome P450

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