A synthetic derivative of native coelenterazine that exhibits 16-fold higher luminescence intensity (emission maximum ~466 nm; half-total time of 0.6-1.2 sec) than native coelenterazine

Coelenterazine h – 1 mg

Brand:
Cayman
CAS:
50909-86-9
Storage:
-20
UN-No:
Non-Hazardous - /

Coelenterazine (Item No. 16123) is a luciferin, a light-emitting biomolecule that serves as a substrate for luciferases or as a constituent of photoproteins, including aequorin.{22804} Coelenterazine can be used to reconstitute the aequorin complex both in vivo and in vitro, emitting blue light when bound to calcium ions. Coelenterazine h is a synthetic derivative of native coelenterazine that exhibits 16-fold higher luminescence intensity (emission maximum ~466 nm; half-total time of 0.6-1.2 sec) than native coelenterazine.{6107} Aequorin complexes reconstituted with coelenterazine h are reported to be more sensitive to calcium ions than those employing the native constituent, providing a useful indicator for small changes in Ca2+ concentrations.{27442}  

 

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Description

A synthetic derivative of native coelenterazine that exhibits 16-fold higher luminescence intensity (emission maximum ~466 nm; half-total time of 0.6-1.2 sec) than native coelenterazine

Formal name: 6-(4-hydroxyphenyl)-2,8-bis(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one

Synonyms:  2-deoxy Coelenterazine|Luciferin (Renilla)

Molecular weight: 407.5

CAS: 50909-86-9

Purity: ≥95%

Formulation: A crystalline solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area

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