A form of the sugar Neu5Ac O-linked with the nucleotide CMP; serves as the substrate for sialyltransferases

CMP-Sialic Acid (sodium salt) – 5 mg

Brand:
Cayman
CAS:
1007117-62-5
Storage:
-20
UN-No:
Non-Hazardous - /

CMP-Sialic acid is a form of the sugar N-acetylneuraminic acid (Neu5Ac) O-linked with the nucleotide cytidine-5’-monophosphate (CMP). In vertebrates, it is biosynthesized within the nucleus from CTP and Neu5Ac by CMP-sialic acid synthetases.{26786} Sialyltransferases transfer Neu5Ac from CMP-sialic acid to various acceptor substrates, most commonly at terminal positions of the oligosaccharide component of glycoproteins or glycolipids.{26788,26784} Sialic acid-containing glycans at the cell surface play important roles in cell interactions and have roles in infection, inflammation, and cancer.{26784,26785,26787}  

 

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Description

A form of the sugar Neu5Ac O-linked with the nucleotide CMP; serves as the substrate for sialyltransferases, which transfer Neu5Ac from CMP-sialic acid to various acceptor substrates, most commonly at terminal positions of the oligosaccharide component of glycoproteins or glycolipids

Formal name: N-acetyl-2-(hydrogen 5′-cytidylate)-β-neuraminic acid, monosodium salt

Synonyms:  CMP-Neu5Ac

Molecular weight: 636.4

CAS: 1007117-62-5

Purity: ≥85%

Formulation: A crystalline solid

Product Type|Biochemicals|Nucleotides/Nucleosides||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism||Research Area|Immunology & Inflammation||Research Area|Infectious Disease

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