A hypolipidemic agent; inhibits HMG-CoA reductase (IC50 = 0.47 mM); stimulates the S-indan-1-ol dehydrogenase activity of human liver AKR 1C4; reduces serum cholesterol and triglyceride levels in rats fed a normal chow pellet diet or a semisynthetic diet containing sucrose as the only carbohydrate source at 10 and 30 mg/kg

Clinofibrate – 100 mg

Brand:
Cayman
CAS:
30299-08-2
Storage:
-20
UN-No:
Non-Hazardous - /

Clinofibrate is a hypolipidemic agent.{57093} It inhibits HMG-CoA reductase (IC50 = 0.47 mM) and stimulates the S-indan-1-ol dehydrogenase activity of the human liver 3α-hydroxysteroid dehydrogenase isoform AKR 1C4 in a concentration-dependent manner.{57094} Clinofibrate (10 and 30 mg/kg) reduces serum cholesterol and triglyceride levels in rats fed a normal chow pellet diet or a semisynthetic diet containing sucrose as the only carbohydrate source.  

 

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SKU: 31109 - 100 mg Category:

Description

A hypolipidemic agent; inhibits HMG-CoA reductase (IC50 = 0.47 mM); stimulates the S-indan-1-ol dehydrogenase activity of human liver AKR 1C4; reduces serum cholesterol and triglyceride levels in rats fed a normal chow pellet diet or a semisynthetic diet containing sucrose as the only carbohydrate source at 10 and 30 mg/kg

Formal name: 2,2′-[cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl-butanoic acid

Synonyms:  S-8527

Molecular weight: 468.6

CAS: 30299-08-2

Purity: ≥95%

Formulation: A crystalline solid

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