A polyphenol antioxidant; inhibits lipid peroxidation in vitro (IC50 = 2.25 µM); improves wound healing in mice; COX-2 inhibitor with 19

Cinnamtannin B-1 – 10 mg

Brand:
Cayman
CAS:
88082-60-4
Storage:
-20
UN-No:
Non-Hazardous - /

Cinnamtannin B-1 is a proanthocyanidin polyphenol originally isolated from cinnamon bark that has antioxidant properties.{34296} Cinnamtannin B-1 has antioxidant properties in vitro, including inhibition of lipid peroxidation (IC50 = 2.25 µM).{34295} It also protects astrocytes and increases proliferation in an in vitro model of ischemia/reperfusion injury.{34293} In mice, it enhances migration of mesenchymal stem cells and improves wound healing.{34294} It exhibits COX-2 inhibition with 19, 27, and 86% inhibition in Sf9 cells at 10, 100, and 1,000 µg/ml, respectively.{34296}  

 

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Description

A polyphenol antioxidant; inhibits lipid peroxidation in vitro (IC50 = 2.25 µM); improves wound healing in mice; COX-2 inhibitor with 19, 27, and 86% inhibition in Sf9 cells at 10, 100, and 1,000 µg/ml, respectively

Formal name: (2R,3R,4S,8S,14R,15R)-2,8-bis(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-8-yl]-3,4-dihydro-8,14-methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol

Synonyms:  LDN-0022358

Molecular weight: 864.8

CAS: 88082-60-4

Purity: ≥85%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Neuroscience|Neuroprotection|Ischemia||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation

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