An FXR ligand; inhibits binding of a SRC-1-based synthetic peptide to FXR (EC50 = 50 = ≥100 nM)

Cilofexor – 10 mg

Brand:
Cayman
CAS:
1418274-28-8
Storage:
-20
UN-No:
Non-Hazardous - /

Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC50 = 50 = ≥100 nM).  

 

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SKU: 25747 - 10 mg Category:

Description

An FXR ligand; inhibits binding of a SRC-1-based synthetic peptide to FXR (EC50 = 50 = ≥100 nM)

Formal name: 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid

Synonyms: 

Molecular weight: 586.9

CAS: 1418274-28-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Bile Acids & Microbiome||Research Area|Endocrinology & Metabolism|Hormones & Receptors|FXRs & LXRs

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