An antibiotic isolated from a strain of Streptomyces; inhibits DNA synthesis in bacteria and suppresses the growth of transplantable tumors in mice.

Chrysomycin A – 1 mg

Brand:
Cayman
CAS:
82196-88-1
Storage:
-20
UN-No:
Non-Hazardous - /

Chrysomycin A is an antibiotic isolated from a strain of Streptomyces.{22201} It is structurally very similar to gilvocarcin V, an inhibitor of topoisomerase II which promotes DNA cross-linking with histone 3 and GRP78 when photoactivated by near-UV light.{22203,22198,22200} Chrysomycin A inhibits DNA synthesis in bacteria and suppresses the growth of transplantable tumors in mice.{22202,22199}  

 

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Description

An antibiotic isolated from a strain of Streptomyces; inhibits DNA synthesis in bacteria and suppresses the growth of transplantable tumors in mice.

Formal name: 4-(6-deoxy-3-C-methyl-β-gulopyranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one

Synonyms:  Albacarcin V|NSC 613946|Virenomycin V

Molecular weight: 508.5

CAS: 82196-88-1

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cancer||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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