A cholesterol ester with anticancer activity; inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells at 50 and 150 μM

Cholesteryl Hemisuccinate – 25 g

Brand:
Cayman
CAS:
1510-21-0
Storage:
-20
UN-No:
Non-Hazardous - /

Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity.{36854} It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively.{36854} Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes.{36855} It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.{24443,36856,36857}  

 

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SKU: 25698 - 25 g Category:

Description

A cholesterol ester with anticancer activity; inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells at 50 and 150 μM, respectively; an ionizable anionic detergent commonly used to stabilize unilamellar vesicles and liposomes; has been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins as well as erythrocyte ghosts

Formal name: (3β)-cholest-5-en-3-ol 3-(hydrogen butanedioate)

Synonyms:  Cholesteryl hydrogen succinate

Molecular weight: 486.7

CAS: 1510-21-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lab Reagents|Detergents||Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Cancer||Research Area|Lipid Biochemistry|Sterol Lipids

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