Cholesteryl docosapentaenoate is a cholesterol ester. It is elevated in liver, plasma, and skeletal muscle of acyl-CoA binding protein (ACBP) knockout mice compared with homozygous controls.{43233}
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A cholesterol ester; elevated in liver, plasma, and skeletal muscle of ACBP knockout mice
Formal name: cholest-5-en-3β-ol, 3-[(7Z,10Z,13Z,16Z,19Z)-7,10,13,16,19-docosapentaenoate]
Synonyms:
Molecular weight: 699.1
CAS: 70110-49-5
Purity: ≥95%
Formulation: A solution in chloroform
Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Lipid Biochemistry|Sterol Lipids
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The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 µM compared to 20 µM by resveratrol.{14545}
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1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.{14480,24261,14478,14479} It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.{14478} Incorporation of glycosphingolipid antigens into DPPC-containing liposomes increases the immunogenicity of the antigens in mice.{14479}
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