A glycosylated derivative of cholesterol; activates Hsf1 in TIG-3 human fetal lung fibroblasts; prevents ulcer formation following cold-restraint stress and increases Hsf1 activity

Cholesterol β-D-Glucoside – 10 mg

Brand:
Cayman
CAS:
7073-61-2
Storage:
-20
UN-No:
Non-Hazardous - /

Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose (Item No. 16775). It is formed from cholesterol and glucosylceramide by β-glucosidase 1.{47305} It activates heat shock transcription factor 1 (Hsf1) in response to heat shock, which increases the expression of heat shock protein 70 (Hsp70) in TIG-3 human fetal lung fibroblasts when used at a concentration of 10 µM.{47306} Cholesterol β-D-glucoside (100 mg/kg) prevents ulcer formation following cold-restraint stress and increases Hsf1 activity, as well as Hsp70 expression and protein levels in rat gastric mucosa.{47307} [Matreya, LLC. Catalog No. 1940]  

 

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SKU: 26713 - 10 mg Category:

Description

A glycosylated derivative of cholesterol; activates Hsf1 in TIG-3 human fetal lung fibroblasts; prevents ulcer formation following cold-restraint stress and increases Hsf1 activity, as well as Hsp70 expression and protein levels in rat gastric mucosa

Formal name: cholest-5-en-3β-yl, β-D-glucopyranoside

Synonyms:  Cholesteryl Glucoside|GluChol|Glucosyl Cholesterol|β-ChlGlc

Molecular weight: 548.8

CAS: 7073-61-2

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Small Molecule Activators|Transcription Factors & Coactivators||Research Area|Immunology & Inflammation|Gastric Disease|Peptic Ulcers

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