A neonicotinoid insecticide; binds to nAChRs (IC50 = 0.6 nM for housefly head membranes); activates non-desensitizing nAChRs in cockroach neurons in vitro (IC50 = 1

Chlothianidin – 100 mg

Brand:
Cayman
CAS:
210880-92-5
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Clothianidin is a neonicotinoid insecticide.{45017} It binds to nicotinic acetylcholine receptors (nAChRs; IC50 = 0.6 nM for housefly head membranes) and activates non-desensitizing nAChRs in cockroach neurons in vitro (IC50 = 1,520 nM). Clothianidin induces mortality in adult M. persicae (LC95 = 1.28 mg/L), as well as H. virescens and S. frugiperda second instar larvae when used at a concentration of 8 mg/L in a leaf-dip bioassay. In vivo, clothianidin (>25 mg/kg) increases the number of premature births in rabbits and reduces the length and weight of fathead minnows (P. promelas) when administered in tank water at a concentration of 20 mg/L.{53371}  

 

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Description

A neonicotinoid insecticide; binds to nAChRs (IC50 = 0.6 nM for housefly head membranes); activates non-desensitizing nAChRs in cockroach neurons in vitro (IC50 = 1,520 nM); induces mortality in adult M. persicae (LC95 = 1.28 mg/L), as well as H. virescens and S. frugiperda second instar larvae at 8 mg/L in a leaf-dip bioassay; increases the number of premature births in rabbits at >25 mg/kg; reduces the length and weight of fathead minnows when administered in tank water at 20 mg/L

Formal name: [C(E)]-N-[(2-chloro-5-thiazolyl)methyl]-N′-methyl-N′′-nitro-guanidine

Synonyms: 

Molecular weight: 249.7

CAS: 210880-92-5

Purity: ≥98%

Formulation: A crystalline solid

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