Description
A broad-spectrum tetracycline antibiotic; inhibits growth of both Gram-positive and Gram-negative bacteria at a range of 0.1-100 μg/ml against A. aerogenes, D. pneumoniae, E. coli, K. pneumoniae, P. morganii, and several species of Hemophilus, Neisseria, Salmonella, and Staphylococcus; protects mice from infection by S. aureus (PD50s = 0.2-7.5 mg/kg for various strains), E. coli (PD50 = 3 mg/kg), and K. pneumoniae (PD50 = 75 mg/kg); an ionophore that is selective for calcium over sodium, potassium, magnesium, strontium, and barium
Formal name: (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
Synonyms: 7-Chlortetracycline
Molecular weight: 478.9
CAS: 57-62-5
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Antibiotics|Tetracyclines||Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Food-borne Illnesses||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia
