A muscle relaxant; induces paralysis in mice

Chlormezanone – 500 mg

Brand:
Cayman
CAS:
80-77-3
Storage:
-20
UN-No:
Non-Hazardous - /

Chlormezanone is a centrally acting muscle relaxant.{43296} It induces paralysis in mice, guinea pigs, dogs, cats, and monkeys (EC50s = 133, <200, 100-250, 50, and 50 mg/kg, respectively). Chlormezanone increases ataxia induced by pentobarbital and alcohol in mice and blocks the crossed extensor reflex of the spine without affecting the knee-jerk reflex in cats. It also induces head drop in rabbits.  

 

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SKU: 25716 - 500 mg Category:

Description

A muscle relaxant; induces paralysis in mice, guinea pigs, dogs, cats, and monkeys (EC50s = 133, <200, 100-250, 50, and 50 mg/kg, respectively); increases ataxia induced by pentobarbital and alcohol in mice; blocks the crossed extensor reflex of the spine without affecting the knee-jerk reflex in cats; induces head drop in rabbits

Formal name: 2-(4-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one, 1,1-dioxide

Synonyms:  (±)-Chlormezanone|NSC 169108

Molecular weight: 273.7

CAS: 80-77-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Neuroscience

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