A fungal metabolite; active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml); cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml); inhibits the growth of multidrug-resistant isolates of E. coli

Chevalone C – 5 mg

Brand:
Cayman
CAS:
1318025-77-2
Storage:
-20
UN-No:
Non-Hazardous - /

Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri.{41778} It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml). Chevalone C inhibits the growth of multidrug-resistant isolates of E. coli, S. aureus, and E. faecium in a disc diffusion assay when used at a concentration of 15 μg/disc.{41304} It also induces cell death in HCT116 colorectal carcinoma cells.{41779}  

 

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SKU: 25084 - 5 mg Category:

Description

A fungal metabolite; active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml); cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml); inhibits the growth of multidrug-resistant isolates of E. coli, S. aureus, and E. faecium at 15 μg/disc; induces cell death in HCT116 colorectal carcinoma cells

Formal name: (2S,4aR,4bR,6aS,12aS,12bR,14aR)-2-(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-1H,11H-phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one

Synonyms: 

Molecular weight: 456.6

CAS: 1318025-77-2

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Natural Products|Terpenes||Research Area|Cancer|Cell Death||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis

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