A potent

CGS 21680 (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
124431-80-7
Storage:
-20
UN-No:
Non-Hazardous - /

CGS 21680 is a potent, selective agonist of the adenosine A2A receptor (Ki = 11-46 nM).{27928,27924} It is less effective at adenosine A1 and A3 receptors (Kis = 0.5-3.1 and 0.6-1 µM, respectively) and is without effect at adenosine A2B (Ki > 10 µM).{27924,27925,27926,27927} CGS 21680 is commonly used to study the actions of the adenosine A2A receptor in cells and tissues.{11819,5049,27816}  

 

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Description

A potent, selective agonist of the adenosine A2A receptor (Ki = 11-46 nM); less effective at adenosine A1 and A3 receptors (Kis = 0.5-3.1 and 0.6-1 µM, respectively) and is without effect at adenosine A2B (Ki > 10 µM)

Formal name: 4-[2-[[6-amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-benzenepropanoic acid, monohydrochloride

Synonyms: 

Molecular weight: 536

CAS: 124431-80-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience

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