A muscarinic receptor agonist (EC50s = 23

Cevimeline (hydrochloride) – 1 mg

Brand:
Cayman
CAS:
107220-28-0
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Cevimeline is a muscarinic receptor agonist (EC50s = 23, 48, and 63 nM for M1, M3, and M5, respectively, and >1 µM for M2 and M4).{19164} It stimulates secretion by salivary glands and is useful in ameliorating xerostomia (dry mouth).{28988,28989}  

 

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Description

A muscarinic receptor agonist (EC50s = 23, 48, and 63 nM for M1, M3, and M5, respectively, and >1 µM for M2 and M4); stimulates secretion by salivary glands and is useful in ameliorating xerostomia (dry mouth)

Formal name: (2’R,3R)-rel-2’-methyl-spiro[1-azabicyclo[2.2.2]octane-3,5’-[1,3]oxathiolane], monohydrochloride

Synonyms:  AF 102B|SNI 2011|SNK 508

Molecular weight: 235.8

CAS: 107220-28-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience

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