A cephalosporin antibiotic; has broad-spectrum activity against Gram-positive and Gram-negative bacteria (mean MICs = 0.005-8.2 μg/ml); inhibits peptidoglycan crosslinking and bacterial cell wall synthesis; resistant to hydrolysis by bacterial β-lactamases; protective against Gram-positive and Gram-negative infections in vivo (mean ED50s = 2 to 35 and 1 to 55 mg/kg

Cefuroxime (sodium salt) – 1 g

Brand:
Cayman
CAS:
56238-63-2
Storage:
-20
UN-No:
Non-Hazardous - /

Cefuroxime is a cephalosporin antibiotic with broad-spectrum activity against Gram-positive and Gram-negative bacteria including S. pyogenes, S. pneumoniae, S. viridans, E. coli, P. mirabilis, H. influenzae, and N. gonorrhoeae (mean MICs = 0.005-8.2 μg/ml).{40366} Like other cephalosporins, cefuroxime inhibits peptidoglycan crosslinking and bacterial cell wall synthesis.{40367} It is resistant to hydrolysis by bacterial β-lactamases, increasing its efficacy against β-lactamase producing Gram-negative bacteria.{40368} Cefuroxime is protective against Gram-positive and Gram-negative infections in vivo with mean ED50 values ranging from 2 to 35 and 1 to 55 mg/kg, in mice and rats, respectively.{40369} Formulations containing cefuroxime have been used to treat urinary tract infections.{40370}  

 

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SKU: 23627 - 1 g Category:

Description

A cephalosporin antibiotic; has broad-spectrum activity against Gram-positive and Gram-negative bacteria (mean MICs = 0.005-8.2 μg/ml); inhibits peptidoglycan crosslinking and bacterial cell wall synthesis; resistant to hydrolysis by bacterial β-lactamases; protective against Gram-positive and Gram-negative infections in vivo (mean ED50s = 2 to 35 and 1 to 55 mg/kg, in mice and rats, respectively)

Formal name: (6R,7R)-3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt

Synonyms: 

Molecular weight: 446.4

CAS: 56238-63-2

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antibiotics|Cephalosporins||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|STDs

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