A cephalosporin antibiotic; active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml); inhibits the growth of clinical isolates of S. aureus

Cefazolin (sodium salt) – 500 mg

Brand:
Cayman
CAS:
27164-46-1
Storage:
-20
UN-No:
Non-Hazardous - /

Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml).{25759} It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50s = <0.09-1.78, 0.44-3.63, and 2.31-5.2 mg/animal, respectively). Formulations containing cefazolin have been used to treat a variety of bacterial infections.  

 

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Description

A cephalosporin antibiotic; active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml); inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml); protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50s = <0.09-1.78, 0.44-3.63, and 2.31-5.2 mg/animal, respectively)

Formal name: (6R)-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7R-[[2-(1H-tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt

Synonyms:  NSC 291561|SKF 41558

Molecular weight: 476.5

CAS: 27164-46-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Cephalosporins||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia

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