Description
CD37 is a type III transmembrane glycoprotein (Mr = 40-52 kDa). The leukocyte-specific protein CD37 is a member of the tetraspanin superfamily, originally described as a cell surface glycoprotein expressed on mature human B cells, but not on pro-B cells or plasma cells.{13049,13050} T cells and monocytes express CD37 at low levels. In humans, CD37 expression is restricted to B and T lymphocytes, monocytes, macrophages, neutrophils, dendritic cells, and certain leukocyte-derived malignant cells. CD37 is not expressed by NK cells, platelets, or erythrocytes.{13048} CD37 monoclonal antibody is recommended for immunophenotyping of B cell neoplasia (B cell chronic lymphocytic leukemia, hairy cell leukemia, and B cell non-Hodgkin’s lymphomas). Human, rat, and murine CD37 sequences have been identified.{13051,13052}
Synonyms:
Immunogen:
Formulation: 100 µg of affinity-purified IgG2b in 500 µl PBS, pH 7.2, containing 0.02% sodium azide
Isotype:
Applications: (+) FC, ICC, and IHC (formalin-fixed paraffin-embedded tissue and frozen sections); (−) WB
Origin: Animal/Mouse
Stability: 365 days
Application|Flow Cytometry||Application|Immunocytochemistry||Application|Immunohistochemistry||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cancer||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity
