Immunogen: Synthetic peptide from an internal region of human CD36 • Host: Rabbit • Species Reactivity: (+) Human

CD36 Polyclonal Antibody – 1 ea

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Cayman
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CD36 is a type-B scavenger receptor that is necessary for the formation of foam cells in atherosclerotic lesions.{7719,9800,9801,9795} This membrane glycoprotein can internalize fatty acids which activate PPARγ and stimulate further expression of CD36.{9798,8499} This positive feedback loop combined with the murine CD36 knock-out studies reinforces the importance of CD36 in lipid metabolism. Additionally CD36 is needed for the phagocytosis of P. falciparum infected erythrocytes, retinal pigment epithelial cell photoreceptor fragments, and post-apoptotic monocytes and neutrophils.{9794,9310,9793,9791} CD36 expression has been monitored during hematopoietic cell differentiation and may be an indicator of tumor spreading in lymphocytic leukemia.{9797} This transmembrane glycoprotein is detected by immunoblotting at 88 kDa or 54 kDa depending on the degree of glycosylation of the receptor in your sample. Positive controls include adipose and heart tissue, platelets, and macrophages.  

 

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SKU: 100011 - 1 ea Category:

Description

Immunogen: Synthetic peptide from an internal region of human CD36 • Host: Rabbit • Species Reactivity: (+) Human, mouse, and rat CD36 • Application(s): IHC and WB • Functioning as a receptor for oxidized LDL, CD36 is a type-B scavenger receptor that is necessary for the formation of foam cells in atherosclerotic lesions.

Synonyms: GPIIIb|GPIV|Hexarelin Receptor|oxLDL Receptor|Thrombospondin Receptor

Immunogen: Synthetic peptide from an internal region of human CD36

Formulation: 500 µl of peptide affinity-purified antibody.

Isotype:

Applications: IHC and WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cardiovascular System|Blood|Erythrocytes & Hemoglobin||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Immunology & Inflammation|Innate Immunity|Phagocytosis||Research Area|Infectious Disease|Parasitic Diseases|Malaria||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation

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