Description
Revealing the molecular signals involved in B and T cell activation is critical to the future discovery of therapeutics that can augment cell-mediated immune responses to disease.{12747,12749,12748} CD150 is a type I transmembrane glycoprotein that is involved in signal transduction of antigen specific responses in B and T cells. It is expressed by activated B cells isolated from tonsils and peripheral blood, B cells in germinal centers and mantle zone of lymph nodes, immature thymocytes, and CD45RO+CD45RA- subpopulation of T cells.{12746,12772} This antibody has been used to detect CD150 in neoplastic cells from diffuse large B-cell lymphoma, Hodgkin’s disease, hairy cell leukemia, and some tumors of ectodermal origin.{12771}
Synonyms: CDw150|IPO-3|SLAM
Immunogen:
Formulation: 100 µg of purified IgG1 in 100 µl PBS, pH 7.2
Isotype:
Applications: FC, ICC, IHC (frozen sections), and IP; may also be used for receptor ligation experiments{12747,12749}
Origin: Animal/Mouse
Stability: 365 days
Application|Flow Cytometry||Application|Immunocytochemistry||Application|Immunohistochemistry||Application|Immunoprecipitation||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cancer||Research Area|Immunology & Inflammation|Adaptive Immunity
