A fluorescent molecular rotor characterized by low background fluorescence

CCVJ – 1 mg

Brand:
Cayman
CAS:
142978-18-5
Storage:
-20
UN-No:
Non-Hazardous - /

Fluorescent molecular rotors are molecules whose fluorescence is inversely proportional to its intramolecular rotation.{28886} The intramolecular rotation of these probes, and hence their fluorescence, depends on the immediate microenvironment of the probe.{28886} As a result, fluorescent molecular rotors are used to evaluate changes in solution and membrane viscosity, polymerization or aggregation processes, and protein (un)folding.{28885,28888,28887} CCVJ is a fluorescent molecular rotor characterized by low background fluorescence, low fluorescence anisotropy, and good water solubility.{28886,28887,28884,28889} Moreover, CCVJ has large hydrophobic structures, allowing it to associate in a non-covalent manner with hydrophobic pockets in proteins in solution.{28886} CCVJ is broadly used to monitor changes in solution and molecular characteristics.{28886,28887,28884}  

 

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Description

A fluorescent molecular rotor characterized by low background fluorescence, low fluorescence anisotropy, and good water solubility; its large hydrophobic structures allow it to associate in a non-covalent manner with hydrophobic pockets in proteins in solution

Formal name: 2-cyano-3-(2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizin-9-yl)-2-propenoic acid

Synonyms:  ​9-(2-Carboxy-2-cyanovinyl)julolidine​

Molecular weight: 268.3

CAS: 142978-18-5

Purity: ≥95%

Formulation: A crystalline solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes

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