An inhibitor of the HAT PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM)

CAY10669 – 10 mg

Brand:
Cayman
CAS:
1243583-88-1
Storage:
-20
UN-No:
Non-Hazardous - /

CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM), displaying a 2-fold improvement in inhibitory potency over anacardic acid (Item No. 13144).{19657} At 30-60 μM, CAY10669 can dose-dependently inhibit histone H4 acetylation in HepG2 cells in vitro.{19657}  

 

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SKU: 10974 - 10 mg Category:

Description

An inhibitor of the HAT PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM), displaying a 2-fold improvement in inhibitory potency over anacardic acid; dose dependently inhibits histone H4 acetylation in HepG2 cells in vitro at 30-60 μM

Formal name: 2-hydroxy-6-[(1Z)-2-[4-(pentyloxy)phenyl]ethenyl]-benzoic acid

Synonyms: 

Molecular weight: 326.4

CAS: 1243583-88-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Acetyltransferases||Research Area|Epigenetics, Transcription, & Translation|Writers|Histone Acetylation

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