An analog of resveratrol which potently induces apoptosis in HL-60 cells (IC50 = 40 nM versus 50 µM for resveratrol); induces apoptosis (IC50 = 30 nM) in HL-60R cells

CAY10616 – 1 mg

Brand:
Cayman
CAS:
586410-08-4
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Resveratrol is a natural polyphenolic antioxidant that has anti-cancer properties. CAY10616 is an analog of resveratrol which potently induces apoptosis in promyelocytic leukemia HL-60 cells (IC50 = 40 nM, vs. 50 μM for resveratrol).{17129} In addition, CAY10599 induces apoptosis (IC50 = 30 nM) in HL-60R, a cell line derived from HL-60 that expresses a multidrug-resistance phenotype (resistant to daunorubicin, etoposide, and citarabine).{17129}  

 

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Description

An analog of resveratrol which potently induces apoptosis in HL-60 cells (IC50 = 40 nM versus 50 µM for resveratrol); induces apoptosis (IC50 = 30 nM) in HL-60R cells, a multidrug-resistant cell line derived from HL-60 cells

Formal name: 5-[(1Z)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxy-phenol

Synonyms: 

Molecular weight: 286.3

CAS: 586410-08-4

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Death|Apoptosis

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