Description
A potent inhibitor of PI3Kγ, selectively inhibiting the γ isoform (IC50 = 30 nM) better than the α, β, and δ isoforms (IC50 = 0.94, 20, and 20 μM, respectively); inhibits phosphorylation of PKB/Akt in mouse macrophages (IC50 = 228 nM)
Formal name: 5-[[5-(4-fluorophenyl)-2-furanyl]methylene]-2,4-thiazolidinedione
Synonyms:
Molecular weight: 289.3
CAS: 328960-84-5
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Kinase Inhibitors|CK2||Product Type|Biochemicals|Kinase Inhibitors|PI3K||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|PI3K/Akt/mTOR Signaling||Research Area|Immunology & Inflammation|Innate Immunity
