A labeled analog of AEA that is non-fluorescent when outside the cell but upon transport into the cell

CAY10455 – 500 µg

Brand:
Cayman
CAS:
290374-09-3
Storage:
-20
UN-No:
De Minimis - 1231 / 3

CAY10455 is a labeled analog of arachidonoyl ethanolamide (anandamide; AEA) that is non-fluorescent when outside the cell. Upon transport into the cell interior, it is cleaved by esterases to give a bright fluorescence at 530 nm.{11827} CAY10455 uptake into C6 glioma cells is inhibited by AEA and its analogs, and conversely CAY10455 inhibits the uptake of tritiated AEA, indicating that they compete for the AEA transporter.{11827}  

 

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SKU: 10005072 - 500 µg Category:

Description

A labeled analog of AEA that is non-fluorescent when outside the cell but upon transport into the cell, is cleaved by esterases to give a bright fluorescence at 530 nm; used as an alternative substrate to study AEA transport via the AEA transporter

Formal name: [3′,6′-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-5-yl]-2-[[1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]amino]ethyl ester carbamic acid

Synonyms:  SKM 4-45-1

Molecular weight: 804.9

CAS: 290374-09-3

Purity: ≥98%

Formulation: A solution in methyl acetate

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Product Type|Biochemicals|Lipids|Fatty Acid Conjugates||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like||Research Area|Lipid Biochemistry|Lipid Transport||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids

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