An NSAID commonly used in animals to combat pain and inflammation

Carprofen – 500 mg

Brand:
Cayman
CAS:
53716-49-7
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used in animals to combat pain and inflammation, particularly as associated with osteoarthritis.{26843,26842} Like many NSAIDs, carprofen inhibits both cyclooxygenases COX-1 and COX-2 (IC50s = 22.3 and 3.9 µM, respectively).{13392,26844} It also inhibits fatty acid amide hydrolase (IC50 = 74 µM), blocking the metabolism of the cannabinoid receptor ligand, arachidonoyl ethanolamide (Item No. 90050).{26844,25933}  

 

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Description

An NSAID commonly used in animals to combat pain and inflammation, particularly as associated with osteoarthritis; inhibits both COX-1 and COX-2 (IC50s = 22.3 and 3.9 µM, respectively) and also FAAH (IC50 = 74 µM)

Formal name: 6-chloro-α-methyl-9H-carbazole-2-acetic acid

Synonyms:  Carprodyl|NSC 297935

Molecular weight: 273.7

CAS: 53716-49-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Product Type|Biochemicals|Small Molecule Inhibitors|Fatty Acid Metabolism||Research Area|Immunology & Inflammation|Arthritis (Non-autoimmune)||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like

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