A metabolite and degradation product of captopril; a potential impurity in commercial preparations of captopril; inhibits angiotensin I-induced increases in mean arterial pressure in anesthetized dogs (ID50 = 0.231 mg/kg

Captopril Disulfide – 10 mg

Brand:
Cayman
CAS:
64806-05-9
Storage:
-20
UN-No:
Non-Hazardous - /

Captopril disulfide is a metabolite and symmetrical disulfide form of the angiotensin converting enzyme (ACE) inhibitor captopril (Item No. 15313).{47405} Captopril disulfide is the main degradation product of captopril and is formed by oxidation.{47406} It is a potential impurity in commercial preparations of captopril. Captopril disulfide inhibits angiotensin I-induced increases in mean arterial pressure in anesthetized dogs (ID50 = 0.231 mg/kg, i.v.).{47407}  

 

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SKU: 28018 - 10 mg Category:

Description

A metabolite and degradation product of captopril; a potential impurity in commercial preparations of captopril; inhibits angiotensin I-induced increases in mean arterial pressure in anesthetized dogs (ID50 = 0.231 mg/kg, i.v.)

Formal name: 1,1′-[dithiobis[(2S)-2-methyl-1-oxo-3,1-propanediyl]]bis-L-proline

Synonyms:  SQ 14551

Molecular weight: 432.6

CAS: 64806-05-9

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Pharmaceutical Impurities||Product Type|Biochemicals|Small Molecule Inhibitors|Angiotensin-converting Enzyme||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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