A carotenoid with diverse biological activities; reduces hydrogen peroxide-induced production of ROS and phosphorylation of ERK and p38 and prevents hydrogen peroxide-induced inhibition of gap junction intercellular communication in WB-F344 rat liver epithelial cells; reduces the number of colonic aberrant crypt foci and preneoplastic lesions in a rat model of N-methylnitrosourea-induced colon carcinogenesis at 0.2 mg/animal; reduces ear edema in a mouse model of TPA-induced inflammation

Capsanthin – 500 µg

Brand:
Cayman
CAS:
465-42-9
Storage:
-20
UN-No:
Non-Hazardous - /

Capsanthin is a carotenoid that has been found in C. annuum and has diverse biological activities.{46052,46053,46054} It reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and phosphorylation of ERK and p38 and prevents hydrogen peroxide-induced inhibition of gap junction intercellular communication in WB-F344 rat liver epithelial cells.{46052} Capsanthin (0.2 mg/animal) reduces the number of colonic aberrant crypt foci and preneoplastic lesions in a rat model of N-methylnitrosourea-induced colon carcinogenesis.{46053} It also reduces ear edema in a mouse model of inflammation induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014).{46054}  

 

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SKU: 31202 - 500 µg Category:

Description

A carotenoid with diverse biological activities; reduces hydrogen peroxide-induced production of ROS and phosphorylation of ERK and p38 and prevents hydrogen peroxide-induced inhibition of gap junction intercellular communication in WB-F344 rat liver epithelial cells; reduces the number of colonic aberrant crypt foci and preneoplastic lesions in a rat model of N-methylnitrosourea-induced colon carcinogenesis at 0.2 mg/animal; reduces ear edema in a mouse model of TPA-induced inflammation

Formal name: (3R,3′S,5′R)-3,3′-dihydroxy-β,κ-caroten-6′-one

Synonyms:  all-trans-Capsanthin

Molecular weight: 584.9

CAS: 465-42-9

Purity: ≥98%

Formulation: A crystalline solid

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