An antihelmintic agent; eradicates S. ratti adult worms from intestine and S. stercoralis larva from muscle at a dose of 50 mg/kg/day; inhibits polymerization of microtubules isolated from bovine brain (IC50 = 64.2 µM)

Cambendazol – 50 mg

Brand:
Cayman
CAS:
26097-80-3
Storage:
-20
UN-No:
Non-Hazardous - /

Cambendazol is an antihelmintic that, at a dose of 50 mg/kg/day in mice, eradicates S. ratti adult worms from intestine and S. stercoralis larva from muscle.{39137} It inhibits polymerization of microtubules isolated from bovine brain with an IC50 value of 64.2 µM.{39138} Formulations containing cambendazol have been used to treat strongyloidiasis in humans and have been studied as potential chemotherapeutics.{39136,39139}  

 

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Description

An antihelmintic agent; eradicates S. ratti adult worms from intestine and S. stercoralis larva from muscle at a dose of 50 mg/kg/day; inhibits polymerization of microtubules isolated from bovine brain (IC50 = 64.2 µM),

Formal name: N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-carbamic acid, 1-methylethyl ester

Synonyms:  Isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate|MK-905|NSC 377071

Molecular weight: 302.4

CAS: 26097-80-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antiparasitics|Anthelmintics||Product Type|Biochemicals|Microtubule Dynamics||Research Area|Cancer||Research Area|Cell Biology|Cytoskeleton & Motor Proteins||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

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