A cell permeable

Calpain Inhibitor II – 1 mg

Brand:
Cayman
CAS:
110115-07-6
Storage:
-20
UN-No:
Non-Hazardous - /

Calpain inhibitor II is a cell permeable, peptide aldehyde inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM).{23731} It has been used to demonstrate the involvement of ubiquitin-proteasome protein degradation in various biological systems.{26048,26049}  

 

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Description

A cell permeable, peptide aldehyde inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM)

Formal name: N-acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide

Synonyms:  Ac-Leu-Leu-Met-H|ALLM

Molecular weight: 401.6

CAS: 110115-07-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases||Research Area|Cell Biology|Proteolysis|Lysosomal Proteases||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System

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