The calcium form of D-glucaric acid; reduces tumor growth in a rat model of mammary tumorigenesis induced by DMBA at 10% w/w; urinary levels have been used as a marker for xenobiotic-induced phase II metabolism in patients with rheumatoid arthritis or individuals exposed to environmental toxicants

Calcium D-Glucarate (hydrate) – 100 g

Brand:
Cayman
CAS:
5793-89-5
Storage:
-20
UN-No:
Non-Hazardous - /

Calcium D-glucarate is the calcium salt form of D-glucaric acid.{52800} D-Glucaric acid is an end product of D-glucuronic acid metabolism in mammals that has also been found in fruits and vegetables and has anticancer activity.{52802} It is produced by the oxidation of D-glucuronic acid and is a precursor in the biosynthesis of the β-glucuronidase inhibitor D-glucaro-1,4-lactone (D-saccharic acid 1,4-lactone; Item No. 18896) in vivo.{52800} Dietary administration of calcium D-glucarate (10% w/w) reduces tumor growth in a rat model of mammary tumorigenesis induced by 7,12-dimethylbenz[a]anthracene (DMBA).{52803} Urinary D-glucaric acid levels have been used as a marker for xenobiotic-induced phase II metabolism in patients with rheumatoid arthritis or individuals exposed to environmental toxicants.{52804,52805}  

 

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Description

The calcium form of D-glucaric acid; reduces tumor growth in a rat model of mammary tumorigenesis induced by DMBA at 10% w/w; urinary levels have been used as a marker for xenobiotic-induced phase II metabolism in patients with rheumatoid arthritis or individuals exposed to environmental toxicants

Formal name: D-glucaric acid calcium salt, monohydrate

Synonyms:  Calcium D-Saccharate|D-Glucaric Acid Calcium Salt|D-Saccharic Acid Calcium Salt

Molecular weight: 320.3

CAS: 5793-89-5

Purity: ≥95%

Formulation: A crystalline solid

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